MovDisordV3, Main, Exploration, bibRecord, 002659

REM behavior disorder, hallucinations and cognitive impairment in Parkinson's disease: A two‐year follow up

Identifieur interne : 002659 ( Main/Exploration ); précédent : 002658; suivant : 002660

REM behavior disorder, hallucinations and cognitive impairment in Parkinson's disease: A two‐year follow up

Auteurs : Elena Sinforiani [Italie] ; Claudio Pacchetti [Italie] ; Roberta Zangaglia [Italie] ; Chiara Pasotti [Italie] ; Raffaele Manni [Italie] ; Giuseppe Nappi [Italie]

Source :

Movement Disorders [ 0885-3185 ] ; 2008-07-30.

RBID : ISTEX:09DA498A5B2D506587C8DC1DEE2F027D6768AE66

Descripteurs français

Pascal (Inist)
- Comportement, Hallucination, Maladie de Parkinson, Pathologie du système nerveux, Trouble cognitif.

English descriptors

KwdEn :
- Age Factors, Aged, Aged, 80 and over, Behavior, Cognition Disorders (diagnosis), Cognition Disorders (epidemiology), Cognition Disorders (etiology), Cognitive disorder, Disease Progression, Female, Follow-Up Studies, Frontal Lobe (physiopathology), Hallucination, Hallucinations (epidemiology), Hallucinations (etiology), Humans, Logic, Male, Memory Disorders (epidemiology), Memory Disorders (etiology), Middle Aged, Nervous system diseases, Neuropsychological Tests, Parkinson Disease (complications), Parkinson Disease (epidemiology), Parkinson Disease (psychology), Parkinson disease, Parkinson's disease, Prognosis, Prospective Studies, RBD, REM Sleep Behavior Disorder (epidemiology), REM Sleep Behavior Disorder (etiology), cognitive impairment, hallucinations.
MESH :
- complications : Parkinson Disease.
- diagnosis : Cognition Disorders.
- epidemiology : Cognition Disorders, Hallucinations, Memory Disorders, Parkinson Disease, REM Sleep Behavior Disorder.
- etiology : Cognition Disorders, Hallucinations, Memory Disorders, REM Sleep Behavior Disorder.
- physiopathology : Frontal Lobe.
- psychology : Parkinson Disease.
- Age Factors, Aged, Aged, 80 and over, Disease Progression, Female, Follow-Up Studies, Humans, Logic, Male, Middle Aged, Neuropsychological Tests, Prognosis, Prospective Studies.

Abstract

In Parkinson's disease (PD) the presence of REM parasonnias as REM Behaviour Disorder (RBD) or vivid dreams/nightmares, is recognized as largely associated with hallucinations, even if the risk of the development of hallucinations seem not to depend on how long the REM parasomnias had been occurring. The aim of this study was to establish if RBDs occurring earlier than hallucinations in PD are predictive of cognitive impairment development. Three groups of PD patients: i) group 1, without RBD and without hallucinations; ii) group 2, with RBD but without hallucinations; iii) group 3, with RBD and hallucinations have been prospectively investigated at baseline and after two years throughout a clinical and neuropsychological evaluation. After two years, the group 1 continued to present normal neuropsychological tests and did not present either RBDs or hallucinations. In the group 2, the frontal impairment evidenced at baseline was confirmed; the onset of newly hallucinations was reported in a subgroup of 12 patients, who proved to be older, with a more severe executive impairment at baseline and with a more severe motor symptoms progression than those RBD patients who had not manifested hallucinations. The group 3, characterized at baseline by a more severe cognitive impairment presented, after two years, a cognitive worsening and a higher mortality rate. The longitudinal but at preliminary step investigation identified a PD subgroup of patients, in whom a common background disease profile, including the presence of RBD, could represent a “red flag” in developing further cognitive impairment. © 2008 Movement Disorder Society

Url:

https://api.istex.fr/document/09DA498A5B2D506587C8DC1DEE2F027D6768AE66/fulltext/pdf

DOI: 10.1002/mds.22126

Affiliations:

Italie

Le document en format XML

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<term>Cognition Disorders (diagnosis)</term>
<term>Cognition Disorders (epidemiology)</term>
<term>Cognition Disorders (etiology)</term>
<term>Cognitive disorder</term>
<term>Disease Progression</term>
<term>Female</term>
<term>Follow-Up Studies</term>
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<term>Hallucinations (epidemiology)</term>
<term>Hallucinations (etiology)</term>
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<term>Logic</term>
<term>Male</term>
<term>Memory Disorders (epidemiology)</term>
<term>Memory Disorders (etiology)</term>
<term>Middle Aged</term>
<term>Nervous system diseases</term>
<term>Neuropsychological Tests</term>
<term>Parkinson Disease (complications)</term>
<term>Parkinson Disease (epidemiology)</term>
<term>Parkinson Disease (psychology)</term>
<term>Parkinson disease</term>
<term>Parkinson's disease</term>
<term>Prognosis</term>
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<term>REM Sleep Behavior Disorder (etiology)</term>
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<front><div type="abstract" xml:lang="en">In Parkinson's disease (PD) the presence of REM parasonnias as REM Behaviour Disorder (RBD) or vivid dreams/nightmares, is recognized as largely associated with hallucinations, even if the risk of the development of hallucinations seem not to depend on how long the REM parasomnias had been occurring. The aim of this study was to establish if RBDs occurring earlier than hallucinations in PD are predictive of cognitive impairment development. Three groups of PD patients: i) group 1, without RBD and without hallucinations; ii) group 2, with RBD but without hallucinations; iii) group 3, with RBD and hallucinations have been prospectively investigated at baseline and after two years throughout a clinical and neuropsychological evaluation. After two years, the group 1 continued to present normal neuropsychological tests and did not present either RBDs or hallucinations. In the group 2, the frontal impairment evidenced at baseline was confirmed; the onset of newly hallucinations was reported in a subgroup of 12 patients, who proved to be older, with a more severe executive impairment at baseline and with a more severe motor symptoms progression than those RBD patients who had not manifested hallucinations. The group 3, characterized at baseline by a more severe cognitive impairment presented, after two years, a cognitive worsening and a higher mortality rate. The longitudinal but at preliminary step investigation identified a PD subgroup of patients, in whom a common background disease profile, including the presence of RBD, could represent a “red flag” in developing further cognitive impairment. © 2008 Movement Disorder Society</div>
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Movement Disorders (revue)

REM behavior disorder, hallucinations and cognitive impairment in Parkinson's disease: A two‐year follow up

REM behavior disorder, hallucinations and cognitive impairment in Parkinson's disease: A two‐year follow up

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.